Thomas Holbech was the 3rd son of William Holbech of Birchingley Hall, baptized 21 October 1606 at Fillingley, Warwickshire.
Admitted pensioner of Emmanuel College, Cambridge, 30 April 1622. Fellow 1629, Master 1675-80, Vice-Chancellor 1677-8. Vicar of Epping, Essex, 1641-3, sequestered, and 1677-8. Prebendary of St Paul's 1660-80. Rector of St Augustine's Church, London (not specified but presumably Watling Street) 1662-80.